Search on: FK506 BINDING PROTEIN 12-RAPAMYCIN ASSOCIATED PROTEIN 1 
Descriptors Found: 1
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Descriptor English:   TOR Serine-Threonine Kinases 
Descriptor Spanish:   Serina-Treonina Quinasas TOR 
Descriptor Portuguese:   Serina-Treonina Quinases TOR 
Synonyms English:   FK506 Binding Protein 12 Rapamycin Associated Protein 1
FK506 Binding Protein 12-Rapamycin Associated Protein 1
FKBP12 Rapamycin Associated Protein
FKBP12 Rapamycin Complex Associated Protein
FKBP12-Rapamycin Associated Protein
FKBP12-Rapamycin Complex-Associated Protein
Kinases, TOR Serine-Threonine
Kinases, mTOR Serine-Threonine
Mammalian Target of Rapamycin
Mechanistic Target of Rapamycin Protein
Protein, RAFT-1
Protein, mTOR
RAFT 1 Protein
RAFT-1 Protein
Rapamycin Target Protein
Serine-Threonine Kinases, TOR
Serine-Threonine Kinases, mTOR
TOR Kinases
TOR Serine Threonine Kinases
Target of Rapamycin Proteins
mTOR Protein
mTOR Serine Threonine Kinases
mTOR Serine-Threonine Kinases  
Tree Number:   D08.811.913.696.620.682.700.931
D12.776.476.925
Definition English:   A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity. 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54051 
Unique Identifier:   D058570 

Occurrence in VHL:
 

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